Some children experienced chest pain and other symptoms.

Pfizer and its partner BioNTech have finally released the results of clinical trials exploring whether their COVID-19 vaccine causes subclinical heart inflammation. The companies found that multiple vaccine recipients suffered heart-related symptoms, but said none met the definition of myocarditis, or heart inflammation.

Researchers with the companies and other institutions analyzed the levels of troponin I, a sign of possible heart damage, in children aged 5 to 30 before and after receipt of the Pfizer-BioNTech vaccine. They also monitored participants for heart-related symptoms, including chest pain. If patients suffered symptoms, doctors examined them and researchers performed other tests, such as an electrocardiogram, as well as additional troponin measurements.

Ten vaccinated participants, including six under the age of 12, reported relevant symptoms. The researchers, though, said none had myocarditis after additional testing.

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