In the first human data linking per- and polyfluoroalkyl substances (PFAS) to thyroid cancer, a study in The Lancet found higher pre-diagnosis blood levels of perfluorooctanesulfonic acid were associated with 56% greater odds of thyroid cancer diagnosis. Several other PFAS chemicals carried a lower but still increased risk.

Exposure to some per- and polyfluoroalkyl substances (PFAS) may increase thyroid cancer risk, according to a study published on Oct. 24.

The analysis, which compared blood samples from 88 people who developed thyroid cancer with samples from people who did not, is the first to document an association between PFAS and thyroid cancer, which had been previously hypothesized.

Past research has linked these endocrine-disrupting chemicals to thyroid disease, a condition in which the gland produces too many or too few hormones.

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