STORY AT-A-GLANCE
Collagen is one-third of the protein in your body and 28% of it is made up of the amino acid glycine. One study estimates most people are about 10 grams short of what their bodies need for all metabolic uses on a daily basis
Mounting research suggests glycine may play an important role in the aging process. It’s been shown to extend lifespan in worms, mice and rats, and improve health in mammalian models of age-related disease
Glycine is a precursor to glutathione, a powerful endogenous antioxidant that declines with age, and the lack of glutathione in older adults may be an element that drives the oxidative stress and mitochondrial dysfunction that lead to age-related degeneration
Glycine also acts as a neurotransmitter and may play an important role in depression, neuroinflammation, neurodegeneration and cognitive decline
Glycine may even be responsible for the epigenetic regulation that drives the aging process. Regulation of the aging process in your mitochondria appears to be ruled by two genes that regulate glycine production in the mitochondria. Adding glycine to the culture medium of fibroblast cells taken from 97-year old people restored the cells’ respiratory function, which suggests that glycine treatment can reverse the age-associated respiration defects in human fibroblasts

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